Regenerative Medicine to Defeat Aging: SENS Research Updates

Aubrey de Grey gives a research update from SENS Research Foundation, which pursues regenerative medicine against aging. He frames aging as the lifelong accumulation of molecular and cellular damage — classifiable into seven categories — and argues that periodically repairing that damage is more tractable than either treating the diseases of old age directly or slowing metabolism itself. He highlights two lines of work: a mouse study showing that clearing accumulated death-resistant cells protected the animals functionally, and SENS’s own project at Rice University to borrow enzymes from soil bacteria that break down oxidized cholesterol, aiming to fix the poisoned “foam cells” that begin cardiovascular disease. He closes by urging the audience to help make aging understood as a legitimate target for medical intervention.

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